Looks like this feature is 'on the way' but not in the main release cycle yet. Found an article that describes the feature being implemented in the development build, #22.
Or at least partially to allow some features to be shortcut-ed Ref: That post mentions an experimental API for more types of actions linked to shortcuts which can be found. Here: Of course that's all in the development stage still. Edit (2018): This is partially possible with the commands api which has been out for a couple years. It's pretty restricted still since you cant replace the ones that are supplied by the browser and im not sure how much is exposed there for things like dev tooling.
Create a shortcut for application on Google Chrome for MacOSX. A shortcut (alias) that would direct to Google Chrome itself? Or a shortcut to open an url directly from desktop? Free service I built that replicates the 'Create Application Shortcuts' behavior on Mac by generating a Chrome Extension of your favorite website. Chrome shortcuts A fast, secure, and free web browser built for the modern web. Chrome syncs bookmarks across all your devices, fills out forms automatically, and so much more.
As described in the comments of, I am also wanting to disable the 'Cmd+Shift+W' shortcut for close window, and incidentally the similar shortcut that appears when I disable the first, which now stands for 'Close All'. I simply went to the Mac's Keyboard preference pane, in the 'Shortcuts' tab, in 'App Shortcuts' section, and went to create new shortcut mappings. I made these for Google Chrome and chose that as the first parameter, but I guess you could fix a similar problem in any other application by selecting the one you want instead. I then proceeded to name the menu entry that I wanted to replace, such as those I mentioned above. Lastly, I assigned it a complex key combination, one that I would hopefully never accidentally press in the future. It's not the best approach, and I am currently reading into which may remove the shortcut completely, but it works well enough through the existing system interface without having to install any additional software as a limited Google Chrome Web Extension or system application.